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Cialis Description

cialis description

Medically reviewed on Feb 1, Cialis is indicated for the treatment of the signs and symptoms of benign prostatic hyperplasia BPH. If Cialis is used with finasteride to initiate BPH treatment, such use is recommended for up to 26 weeks because the incremental benefit of Cialis decreases from 4 weeks until 26 weeks, and the incremental benefit of Cialis beyond 26 weeks is unknown [see Clinical Studies Do not split Cialis tablets; entire dose should be taken.

Concomitant use of nitrates in any form is contraindicated [see Contraindications 4. ED — When Cialis is coadministered with an alpha-blocker in patients being treated for ED, patients should be stable on alpha-blocker therapy prior to initiating treatment, and Cialis should be initiated at the lowest recommended dose [see Warnings and Precautions 5.

Cialis for Once Daily Use — For patients taking concomitant potent inhibitors of CYP3A4, such as ketoconazole or ritonavir, the maximum recommended dose is 2. Four strengths of almond-shaped tablets are available in different sizes and different shades of yellow:. In clinical pharmacology studies, Cialis was shown to potentiate the hypotensive effect of nitrates [see Clinical Pharmacology Hypersensitivity reactions have been reported, including Stevens-Johnson syndrome and exfoliative dermatitis [see Adverse Reactions 6.

Evaluation of erectile dysfunction and BPH should include an appropriate medical assessment to identify potential underlying causes, as well as treatment options.

Physicians should consider the cardiovascular status of their patients, since there is a degree of cardiac risk associated with sexual activity.

Therefore, treatments for erectile dysfunction, including Cialis, should not be used in men for whom sexual activity is inadvisable as a result of their underlying cardiovascular status. Patients who experience symptoms upon initiation of sexual activity should be advised to refrain from further sexual activity and seek immediate medical attention.

Physicians should discuss with patients the appropriate action in the event that they experience anginal chest pain requiring nitroglycerin following intake of Cialis. In such circumstances, nitrates should still only be administered under close medical supervision with appropriate hemodynamic monitoring. Therefore, patients who experience anginal chest pain after taking Cialis should seek immediate medical attention.

Patients with left ventricular outflow obstruction, e. The following groups of patients with cardiovascular disease were not included in clinical safety and efficacy trials for Cialis, and therefore until further information is available, Cialis is not recommended for the following groups of patients:.

As with other PDE5 inhibitors, tadalafil has mild systemic vasodilatory properties that may result in transient decreases in blood pressure. While this effect should not be of consequence in most patients, prior to prescribing Cialis, physicians should carefully consider whether their patients with underlying cardiovascular disease could be affected adversely by such vasodilatory effects. Patients with severely impaired autonomic control of blood pressure may be particularly sensitive to the actions of vasodilators, including PDE5 inhibitors.

Physicians should be aware that Cialis for once daily use provides continuous plasma tadalafil levels and should consider this when evaluating the potential for interactions with medications e.

There have been rare reports of prolonged erections greater than 4 hours and priapism painful erections greater than 6 hours in duration for this class of compounds. Priapism, if not treated promptly, can result in irreversible damage to the erectile tissue.

Patients who have an erection lasting greater than 4 hours, whether painful or not, should seek emergency medical attention. Cialis should be used with caution in patients who have conditions that might predispose them to priapism such as sickle cell anemia, multiple myeloma, or leukemia , or in patients with anatomical deformation of the penis such as angulation, cavernosal fibrosis, or Peyronie's disease.

Physicians should advise patients to stop use of all phosphodiesterase type 5 PDE5 inhibitors, including Cialis, and seek medical attention in the event of a sudden loss of vision in one or both eyes.

Such an event may be a sign of non-arteritic anterior ischemic optic neuropathy NAION , a rare condition and a cause of decreased vision, including permanent loss of vision, that has been reported rarely postmarketing in temporal association with the use of all PDE5 inhibitors.

A similar study reported a consistent result, with a risk estimate of 2. Therefore, PDE5 inhibitors, including Cialis, should be used with caution in these patients and only when the anticipated benefits outweigh the risks. Individuals with "crowded" optic disc are also considered at greater risk for NAION compared to the general population; however, evidence is insufficient to support screening of prospective users of PDE5 inhibitors, including Cialis, for this uncommon condition.

Patients with known hereditary degenerative retinal disorders, including retinitis pigmentosa, were not included in the clinical trials, and use in these patients is not recommended. Physicians should advise patients to stop taking PDE5 inhibitors, including Cialis, and seek prompt medical attention in the event of sudden decrease or loss of hearing.

These events, which may be accompanied by tinnitus and dizziness, have been reported in temporal association to the intake of PDE5 inhibitors, including Cialis. It is not possible to determine whether these events are related directly to the use of PDE5 inhibitors or to other factors [see Adverse Reactions 6.

Physicians should discuss with patients the potential for Cialis to augment the blood-pressure-lowering effect of alpha-blockers and antihypertensive medications [see Drug Interactions 7.

Caution is advised when PDE5 inhibitors are coadministered with alpha-blockers. PDE5 inhibitors, including Cialis, and alpha-adrenergic blocking agents are both vasodilators with blood-pressure-lowering effects. When vasodilators are used in combination, an additive effect on blood pressure may be anticipated.

In some patients, concomitant use of these two drug classes can lower blood pressure significantly [see Drug Interactions 7. Consideration should be given to the following:. Because of insufficient information in patients with severe hepatic impairment, use of Cialis in this group is not recommended [see Use in Specific Populations 8. Cialis for once daily use has not been extensively evaluated in patients with mild or moderate hepatic impairment. Therefore, caution is advised if Cialis for once daily use is prescribed to these patients.

Patients should be made aware that both alcohol and Cialis, a PDE5 inhibitor, act as mild vasodilators. When mild vasodilators are taken in combination, blood-pressure-lowering effects of each individual compound may be increased. Therefore, physicians should inform patients that substantial consumption of alcohol e.

Cialis is metabolized predominantly by CYP3A4 in the liver. In patients taking potent inhibitors of CYP3A4 and Cialis for once daily use, the maximum recommended dose is 2. The safety and efficacy of combinations of Cialis and other PDE5 inhibitors or treatments for erectile dysfunction have not been studied. PDE5 is found in platelets. Cialis has not been administered to patients with bleeding disorders or significant active peptic ulceration.

Although Cialis has not been shown to increase bleeding times in healthy subjects, use in patients with bleeding disorders or significant active peptic ulceration should be based upon a careful risk-benefit assessment and caution.

The use of Cialis offers no protection against sexually transmitted diseases. Counseling patients about the protective measures necessary to guard against sexually transmitted diseases, including Human Immunodeficiency Virus HIV should be considered. Prior to initiating treatment with Cialis for BPH, consideration should be given to other urological conditions that may cause similar symptoms. In addition, prostate cancer and BPH may coexist. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.

Tadalafil was administered to over men during clinical trials worldwide. In trials of Cialis for once daily use, a total of , , and were treated for at least 6 months, 1 year, and 2 years, respectively. For Cialis for use as needed, over and subjects were treated for at least 6 months and 1 year, respectively. In three placebo-controlled clinical trials of 12 or 24 weeks duration, mean age was 58 years range 21 to 82 and the discontinuation rate due to adverse events in patients treated with tadalafil was 4.

The following adverse reactions were reported see Table 2 in clinical trials of 12 weeks duration:. The following adverse reactions were reported see Table 3 over 24 weeks treatment duration in one placebo-controlled clinical study:. In three placebo-controlled clinical trials of 12 weeks duration, two in patients with BPH and one in patients with ED and BPH, the mean age was 63 years range 44 to 93 and the discontinuation rate due to adverse events in patients treated with tadalafil was 3.

Adverse reactions leading to discontinuation reported by at least 2 patients treated with tadalafil included headache, upper abdominal pain, and myalgia. The following adverse reactions were reported see Table 4. Back pain or myalgia was reported at incidence rates described in Tables 1 through 4. In tadalafil clinical pharmacology trials, back pain or myalgia generally occurred 12 to 24 hours after dosing and typically resolved within 48 hours.

When medical treatment was necessary, acetaminophen or non-steroidal anti-inflammatory drugs were generally effective; however, in a small percentage of subjects who required treatment, a mild narcotic e. In the 1-year open label extension study, back pain and myalgia were reported in 5. Diagnostic testing, including measures for inflammation, muscle injury, or renal damage revealed no evidence of medically significant underlying pathology.

Across placebo-controlled studies with Cialis for use as needed for ED, diarrhea was reported more frequently in patients 65 years of age and older who were treated with Cialis 2. A causal relationship of these events to Cialis is uncertain.

Excluded from this list are those events that were minor, those with no plausible relation to drug use, and reports too imprecise to be meaningful:.

Body as a Whole — asthenia, face edema, fatigue, pain, peripheral edema. Cardiovascular — angina pectoris, chest pain, hypotension, myocardial infarction, postural hypotension, palpitations, syncope, tachycardia. Digestive — abnormal liver function tests, dry mouth, dysphagia, esophagitis, gastritis, GGTP increased, loose stools, nausea, upper abdominal pain, vomiting, gastroesophageal reflux disease, hemorrhoidal hemorrhage, rectal hemorrhage.

Nervous — dizziness, hypesthesia, insomnia, paresthesia, somnolence, vertigo. Ophthalmologic — blurred vision, changes in color vision, conjunctivitis including conjunctival hyperemia , eye pain, lacrimation increase, swelling of eyelids. Urogenital — erection increased, spontaneous penile erection. The following adverse reactions have been identified during post approval use of Cialis. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

These events have been chosen for inclusion either due to their seriousness, reporting frequency, lack of clear alternative causation, or a combination of these factors. Cardiovascular and Cerebrovascular — Serious cardiovascular events, including myocardial infarction, sudden cardiac death, stroke, chest pain, palpitations, and tachycardia, have been reported postmarketing in temporal association with the use of tadalafil.

Most, but not all, of these patients had preexisting cardiovascular risk factors. Many of these events were reported to occur during or shortly after sexual activity, and a few were reported to occur shortly after the use of Cialis without sexual activity. Others were reported to have occurred hours to days after the use of Cialis and sexual activity.

It is not possible to determine whether these events are related directly to Cialis, to sexual activity, to the patient's underlying cardiovascular disease, to a combination of these factors, or to other factors [see Warnings and Precautions 5.

Body as a Whole — hypersensitivity reactions including urticaria, Stevens-Johnson syndrome, and exfoliative dermatitis. Nervous — migraine, seizure and seizure recurrence, transient global amnesia. Ophthalmologic — visual field defect, retinal vein occlusion, retinal artery occlusion.

Non-arteritic anterior ischemic optic neuropathy NAION , a cause of decreased vision including permanent loss of vision, has been reported rarely postmarketing in temporal association with the use of PDE5 inhibitors, including Cialis.

Most, but not all, of these patients had underlying anatomic or vascular risk factors for development of NAION, including but not necessarily limited to: Otologic — Cases of sudden decrease or loss of hearing have been reported postmarketing in temporal association with the use of PDE5 inhibitors, including Cialis. In some of the cases, medical conditions and other factors were reported that may have also played a role in the otologic adverse events. In many cases, medical follow-up information was limited.

It is not possible to determine whether these reported events are related directly to the use of Cialis, to the patient's underlying risk factors for hearing loss, a combination of these factors, or to other factors [see Warnings and Precautions 5.

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Cialis description

Cialis, also known as tadalafil or Adcirca, is used to treat erectile dysfunction and pulmonary arterial hypertension. Find out how to use it. Find patient medical information for Cialis Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. DESCRIPTION. CIALIS (tadalafil) is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Tadalafil has.

Cialis description

By clicking Subscribe, I agree to the Drugs, cialis description. Priapism, if not treated promptly, can result in irreversible damage to the erectile tissue. Benign Prostatic Hyperplasia tamsulosinfinasterideFlomaxdoxazosinterazosinprazosintadalafilProscaralfuzosindutasterideCarduraRapafloMore Tadalafil is an annulated 2,5-diketopiperazine. The catechol metabolite undergoes extensive methylation and glucuronidation to form the methylcatechol and methylcatechol glucuronide conjugate, respectively.

Description Buy Cialis 20mg Online Paypal – Regenerate your sexual power: For any solid relationship, it is essential to get the joy of closeness session. You get the harder erection when the chamber penile caversona is loaded with sufficient measure of blood. CIALIS (tadalafil) tablets, for oral use. DESCRIPTION. CIALIS (tadalafil) is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Description Of Cialis CanadianPharmacyOnline. Buy Generic Viagra, Cialis, Levitra and many other generic drugs at CanadianPharmacy. Lowest prices for Generic and Brand drugs. Bonus 10 free pills, discounts and FREE SHIPPING. Cheapest drugs online - buy and save money.

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